Protein found in humans
ZNF334 |
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Identifiers |
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Aliases | ZNF334, zinc finger protein 334 |
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External IDs | MGI: 2388656; HomoloGene: 23076; GeneCards: ZNF334; OMA:ZNF334 - orthologs |
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Gene location (Mouse) |
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| Chr. | Chromosome 2 (mouse)[1] |
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| Band | 2|2 H3 | Start | 165,216,184 bp[1] |
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End | 165,230,179 bp[1] |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- DNA binding
- metal ion binding
- nucleic acid binding
- protein binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | - intracellular anatomical structure
- nucleus
| Biological process | - regulation of transcription, DNA-templated
- transcription, DNA-templated
- regulation of transcription by RNA polymerase II
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001270497 NM_018102 NM_199441 |
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RefSeq (protein) | NP_001257426 NP_060572 NP_001340742 NP_001340743 NP_001340744
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NP_001340745 NP_001340746 NP_001340747 NP_001340748 NP_001340749 NP_001340750 NP_001340751 NP_001340752 NP_001340753 NP_001340754 NP_001340755 NP_955473 |
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Location (UCSC) | n/a | Chr 2: 165.22 – 165.23 Mb |
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PubMed search | [2] | [3] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Zinc finger protein 334 is a protein that in humans is encoded by the ZNF334 gene. [4]
Function
This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
References
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017667 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Zinc finger protein 334". Retrieved 2016-03-10.
Further reading
- Henc I, Soroczyńska-Cybula M, Bryl E, Witkowski JM (2015). "The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people". Acta Biochim. Pol. 62 (1): 113–7. doi:10.18388/abp.2014_857. PMID 25738173.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.