HES5 |
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معرفات |
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أسماء بديلة | HES5, bHLHb38, hes family bHLH transcription factor 5 |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 607348 MGI: MGI:104876 HomoloGene: 7755 GeneCards: 388585 |
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علم الوجود الجيني |
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وظائف جزيئية | • ربط دي إن إي • protein dimerization activity • transcription factor binding • chromatin binding • GO:0001078، GO:0001214، GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • double-stranded DNA binding • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001106 transcription corepressor activity • sequence-specific DNA binding • sequence-specific double-stranded DNA binding |
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مكونات خلوية | • بلازم نووي • نواة • مكون خلوي |
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عمليات حيوية | • Notch signaling pathway • auditory receptor cell fate determination • establishment of epithelial cell polarity • تمايز خلوي • negative regulation of astrocyte differentiation • regulation of inner ear auditory receptor cell differentiation • GO:0009373 ضبط نسخ الدنا • negative regulation of neuron differentiation • inner ear receptor cell stereocilium organization • comma-shaped body morphogenesis • metanephric nephron tubule morphogenesis • chondrocyte differentiation • central nervous system myelination • GO:1901227 negative regulation of transcription by RNA polymerase II • cell maturation • negative regulation of forebrain neuron differentiation • نسخ الدنا • نماء عصبي • negative regulation of stem cell differentiation • neuronal stem cell population maintenance • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated • نمو متعدد الخلايا • glial cell fate commitment • telencephalon development • brain development • inner ear auditory receptor cell differentiation • التصاق الخلايا • astrocyte differentiation • تَكوّن الغُضروف • forebrain radial glial cell differentiation • regulation of myelination • negative regulation of oligodendrocyte differentiation • S-shaped body morphogenesis • neural tube development • neuron differentiation • ضبط زيادي للتكاثر الخلوي • positive regulation of BMP signaling pathway • negative regulation of pro-B cell differentiation • regulation of cell differentiation • smoothened signaling pathway • oligodendrocyte development • camera-type eye development • specification of loop of Henle identity • regulation of epithelial cell proliferation • GO:0045996 negative regulation of transcription, DNA-templated • negative regulation of inner ear receptor cell differentiation • regulation of neurogenesis • positive regulation of receptor signaling pathway via JAK-STAT • positive regulation of Notch signaling pathway • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني • positive regulation of smooth muscle cell proliferation • positive regulation of tyrosine phosphorylation of STAT protein • GO:0034622 protein-containing complex assembly • تكون الجسيدات • central nervous system development • نقل شاردة الكالسيوم • negative regulation of inner ear auditory receptor cell differentiation |
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المصادر:Amigo / QuickGO | |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 388585 | 15208 |
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Ensembl | ENSG00000197921;db=core ENSG00000273529، ENSG00000197921 | ENSMUSG00000048001 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | XM_005244751 NM_001010926، XM_005244751 |
| | XM_006538562، NM_001370755 NM_010419، XM_006538562، NM_001370755 |
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RefSeq (بروتين) | | XP_005244808 NP_001010926، XP_005244808 |
| | XP_006538625، NP_001357684 NP_034549، XP_006538625، NP_001357684 |
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الموقع (UCSC | n/a | Chr 4: 155.05 – 155.05 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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